If peptide synthesis were a high school, solid-phase peptide synthesis (SPPS) would be the valedictorian. Praised for its speed and efficiency, SPPS has become the go-to method for peptide synthesis, especially for smaller peptides. By anchoring amino acids to a solid resin and building the peptide chain step by step, SPPS allows for rapid synthesis and easy purification, streamlining the path from concept to compound.
